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Mobilization of HIV Spread by Diaphanous 2 Dependent Filopodia in ...

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Mobilization of HIV Spread by Diaphanous 2 Dependent Filopodia in ...

Author Summary Dendritic cells represent a unique cell type with respect to HIV, as they are the first point of contact for the virus in the genital mucosa and have the ability to spread virus efficiently in very low numbers to the primary HIV target, CD4 T cells. During the primary immune response, dendritic cells work in small numbers to make numerous and repetitive contacts, in order to filter and communicate with appropriate CD4 T cells. T...

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